βΒ $169 Million market cap Β· β88.5% from peak
The rise & fall
5 moments Β· 2013β2024
The key moments, with employee sentiment along the way.
2013
π±
2013
Founded in Jonathan Rothberg's startup foundry
The DNA-sequencing pioneer's 4Catalyzer incubator sets out to do for proteins what cheap genome sequencing did for DNA.
GenomeWeb
Jun 2021
π
Jun 2021
The peak: a $1.46B SPAC debut$1.46B
Merges with HighCape Capital's SPAC on the back of an oversubscribed $425M PIPE β with the chips still years from market.
GlobeNewswire
2022
π
2022
Slips out of the club
Commercial traction comes slowly, and the pre-revenue premium evaporates as the market turns on biotech-tools SPACs.
GenomeWeb
2022β24
π¬
From the inside Β· Glassdoor reviews, 2022β24
Glassdoor reviews across the slide counted repeated layoff rounds β unusually frequent for a company its size β with employees pointing to shifting priorities and abandoned projects, and describing a leadership team slow to set a clear direction.
Today
Today
Still in the club β and still trading
Live Β· QSI Β· NasdaqGMas of 2026-09-17
$0.77β² 4.19% todayβ $169M cap Β· β88.5% from peak
π¬ entries paraphrase anonymous, unverified reviews posted publicly on Glassdoor β; dated facts carry their source.
How it happened
Quantum-Si is developing semiconductor-chip-based 'next-generation protein sequencing,' aiming to do for proteins what cheap DNA sequencing did for genomics, and went public in June 2021 via a SPAC merger with HighCape Capital at a $1.46B valuation, backed by an oversubscribed $425M PIPE. Commercial traction came slowly and the market soured on pre-revenue biotech-tools SPACs; the stock fell about 88% to around $180M.
Source: GlobeNewswire / GenomeWeb / stockanalysis ($1.46B pro forma equity value via HighCape Capital SPAC, June 2021, ~$425M PIPE; ~$180M market cap by 2026)
Founder
JR
Jonathan Rothberg
Founder & Executive Chairman (interim CEO 2022); current CEO is Jeff Hawkins
Still there β Founder and Chairman Β· LinkedIn β
Current roles as self-reported on LinkedIn, retrieved 2026-08-21. See our methodology.