Quantum-Si

Biotech tools / protein sequencingUSA
πŸ“‰ Public < $1B
PeakΒ $1.46 BillionToday
βˆ’87%
from peak
  1. πŸ¦„
    Became a unicorn
    2021
  2. πŸ“ˆ
    Peak valuation
    $1.46 Billion ’21
  3. πŸ’”
    Became a Unitard
    2022
  4. πŸ’Έ
    Last valuation
    ~$188M
Current status
Public (Nasdaq: QSI); market cap ~$0.18B, down ~88% from its de-SPAC valuation.
Live Β· QSIΒ· NasdaqGM
as of 2026-06-29
$0.862β–Ό 6.44% today
β‰ˆΒ $188 Million market cap Β· βˆ’87.1% from peak

How it happened

Quantum-Si is developing semiconductor-chip-based 'next-generation protein sequencing,' aiming to do for proteins what cheap DNA sequencing did for genomics, and went public in June 2021 via a SPAC merger with HighCape Capital at a $1.46B valuation, backed by an oversubscribed $425M PIPE. Commercial traction came slowly and the market soured on pre-revenue biotech-tools SPACs; the stock fell about 88% to around $180M. Glassdoor reviews across the slide describe the strain internally: employees counted repeated layoff rounds β€” unusually frequent for a company its size β€” and pointed to shifting priorities and abandoned projects, with a number describing leadership as insular and slow to set a clear direction.

Employee accounts paraphrase anonymous, unverified reviews posted publicly on Glassdoor β†—. See our methodology.

Source: GlobeNewswire / GenomeWeb / stockanalysis ($1.46B pro forma equity value via HighCape Capital SPAC, June 2021, ~$425M PIPE; ~$180M market cap by 2026)

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